ΔΗΜΟΣΙΕΥΣΕΙΣ

  1. A. ANGELIS, L. ANTONIADI, P. STATHOPOULOS, M. HALABALAKI, A.-L. SKALTSOUNIS.
    Oleocanthalic and Oleaceinic acids: New compounds from Extra Virgin Olive Oil (EVOO). Phytochemistry Letters, 2018, 26, 190-194. DOI: 10.1016/j.phytol.2018.06.020
  2. O.S. KOUTSONI, K. KARAMPETSOU, I.D. KYRIAZIS, P. STATHOPOULOS, N. ALIGIANNIS, M. HALABALAKI, A.-L. SKALTSOUNIS, E. DOTSIKA.
    Evaluation of total phenolic fraction derived from extra virgin olive oil for its antileishmanial activity. Phytomedicine, 2018, 47, 143-150. https://doi.org/10.1016/j.phymed.2018.04.030
  3. P. KOUKA, G.-A. CHATZIEFFRAIMIDI, G. RAFTIS, D. STAGOS, A. ANGELIS, P. STATHOPOULOS, N. XYNOS, A.-L. SKALTSOUNIS, A.M. TSATSAKIS, D. KOURETAS
    Antioxidant effects of an olive oil total polyphenolic fraction from a Greek Olea europaea variety in different cell cultures. Phytomedicine, 2018, 47, 135-142. DOI: 10.1016/j.phymed.2018.04.054
  4. I. DAGLA, D. BENAKI, E. BAIRA, N. LEMONAKIS, H. POUDYAL, L. BROWN, A. TSARBOPOULOS, A.-L. SKALTSOUNIS, E. MIKROS, E. GIKAS.
    Alteration in the liver metabolome of rats with metabolic syndrome after treatment with Hydroxytyrosol. A Mass Spectrometry and Nuclear Magnetic Resonance-based metabolomics study. Talanta, 2018, 178, 246-257. DOI: 10.1016/j.talanta.2017.09.029
  5. E. NIKOLAIVITS, A. TERMENTZI, A.-L. SKALTSOUNIS, N. FOKIALAKIS, V. TOPAKAS.
    Enzymatic tailoring of oleuropein from Olea europaea leaves and product identification by HRMS/MS spectrometry. Journal of Biotechnology, 2017, 253, 48-54. DOI: 10.1016/j.jbiotec.2017.05.020
  6. P. SAMARA, N. CHRISTOFORIDOU, C. LEMUS, A. ARGYROPOULOU, K. IOANNOU, K. VOUGOGIANNOPOULOU, N. ALIGIANNIS, E. PARONIS, N. GABORIAUD-KOLAR, O. TSITSILONIS, A.-L. SKALTSOUNIS.
    New semi-synthetic analogs of oleuropein show improved anticancer activity in vitro and in vivo Eur. J. Med. Chem. 2017, 137, 11-29. DOI: 10.1016/j.ejmech.2017.05.029
  7. A. ANGELIS, M. HAMZAOUI, N. ALIGIANNIS, TH. NIKOU, D. MICHAILIDIS, P. GEROLIMATOS, A. TERMENTZI, J. HUBE, M. HALABALAKI, J. H. RENAULT, A.-L. SKALTSOUNIS.
    An Integrated Process for the Recovery of High Added-Value Compounds from Olive Oil using Solid Support Free Liquid-Liquid Extraction and Chromatography Techniques Journal of Chromatography A, 2017, 1491, 126-136. DOI:10.1016/j.chroma.2017.02.046
  8. P. KOUKA, A. PRIFTIS, D. STAGOS, A. ANGELIS, P. STATHOPOULOS, N. XYNOS, A.-L. SKALTSOUNIS, CH. MAMOULAKIS, A. M. TSATSA KIS, D. A. SPANDIDOS, D. KOURETAS.
    Assessment of the antioxidant activity of an olive oil total polyphenolic fraction and hydroxytyrosol from a Greek Olea europea variety in endothelial cells and myoblasts. International Journal of Molecular Medicine, 2017, 40, 703-712. DOI: 10.3892/ijmm.2017.3078
  9. N. LEMONAKIS, H. POUDYAL, M. HALABALAKI, L. BROWN, A. TSARBOPOULOS, A.-L. SKALTSOUNIS, E. GIKAS.
    LC-MS-based metabolomics of hydroxytyrosol administration in rats for the reversal of metabolic syndrome. Journal of Chromatography B, 2017, 1041, 45-59. DOI:10.1016/j.jchromb.2016.12.020
  10. H. POUDYAL, N. LEMONAKIS, E. GIKAS, M. HALABALAKI, A.-L. SKALTSOUNIS, L. BROWN.
    Hydroxytyrosol ameliorates metabolic, cardiovascular and liver changes in a rat model of diet-induced metabolic syndrome: pharmacological and metabolism-based investigation. British Journal of Pharmacology, 2017, 117, 32-45. DOI:10.1016/j.phrs.2016.12.002
  11. N. LEMONAKIS, V. MOUGIOS, M. HALABALAKI, A. -L. SKALTSOUNIS, E. GIKAS.
    A novel bioanalytical method based on UHPLC-HRMS/MS for the quantification of oleuropein in human serum. Application to a pharmacokinetic study. Biomedical Chromatography, 2016, 12. DOI:10.1002/bmc.3779
  12. A. PAPACHRISTODOULOU, M. TSOUKALA, D. BENAKI, S. KOSTIDIS, K. GIOTI, N. ALIGIANNIS, H. PRATSINIS, D. KLETSAS, A.-L. SKALTSOUNIS, E. MIKROS, R. TENTA.
    Oleuropein is a Powerful Sensitizer of Doxorubicin-mediated Killing of Prostate Cancer Cells and Exerts Its Action via Induction of Autophagy. Journal of Cancer Research and Treatment, 2016, 4, 61-68.
    DOI: 10.12691/jcrt-4-4-2
  13. V. BOKA, A. ARGYROPOULOU, E. GIKAS, A. ANGELIS, N. ALIGIANNIS, A.-L. SKALTSOUNIS.
    Employment of High-Performance Thin-Layer Chromatography for the Quantification of Oleuropein in Olive Leaves and the Selection of a Suitable Solvent System for Its Isolation with CPC. Planta Medica, 2015, 81, 1628-1635. DOI: 10.1055/s-0035-1558140
  14. N. XYNOS, D. ABATIS, A. ARGYROPOULOU, P. POLYCHRONOPOULOS, N.ALIGIANNIS, A.-L. SKALTSOUNIS.
    Development of a Sustainable Procedure for the Recovery of Hydroxytyrosol from Table Olive Processing Wastewater Using Adsorption Resin Technology and Centrifugal Partition Chromatography. Planta Medica, 2015, 81, 1621-1627. DOI: 10.1055/s-0035-1558111
  15. A.M. KEILER, S. DJIOGUE, T. EHRHARDT, O. ZIERAU, A.-L. SKALTSOUNIS, M.HALABALAKI, G. VOLLMER.
    Oleocanthal Modulates Estradiol-Induced Gene Expression Involving Estrogen Receptor. Planta Medica, 2015, 81, 1263-1269. DOI: 10.1055/s-0035-1546194
  16. K. VOUGOGIANNOPOULOU, M.T. ANGELOPOULOU, H. PRATSINIS, R.GROUGNET, M. HALABALAKI, D. KLETSAS, B. DEGUIN, A.-L. SKALTSOUNIS.
    Chemical and Biological Investigation of Olive Mill Waste Water – OMWW Secoiridoid Lactones. Planta Medica, 2015, 81, 1205-1212. DOI:10.1055/s-0035-1546243
  17. T. MICHEL, I. KHLIF, P. KANAKIS, A. TERMENTZI, N. ALLOUCHE, M.HALABALAKI, A.-L. SKALTSOUNIS.
    UHPLC-DAD-FLD and UHPLC-HRMS/MS based metabolic profiling and characterization of different Olea europaea organs of Koroneiki and Chetoui varieties. Phytochemistry Letters, 2015, 11, 424-439.
    DOI: 10.1016/j.phytol.2014.12.020
  18. I. ANDREADOU, D. BENAKI, P. EFENTAKIS, S.-I. BIBLI, A.-I. MILIONI, A. PAPACHRISTODOULOU, A. ZOGA, A.-L. SKALTSOUNIS, E. MIKROS, E. K.ILIODROMITIS.
    The natural olive constituent oleuropein induces nutritional cardioprotection in normal and cholesterol-fed rabbits: Comparison with preconditioning. Planta Medica, 2015, 81, 655-663. DOI:10.1055/s-0034-1383306
  19. P. EFENTAKIS, E.K ILIODROMITIS, E. MIKROS, A. PAPACHRISTODOULOU, N. DAGRES,
    A.-L. SKALTSONIS, I. ANDREADOU.
    Effects of the olive tree leaf constituents on myocardial oxidative damage and atherosclerosis. Planta Medica, 2015, 81, 648-654. DOI:10.1055/s-0035-1546017
  20. K. MNAFGUI, I. KHLIF, R. HAJJI, F. DERBALI, F. KRAIEM, H. ELLEFI, T. MICHEL, M. HALABALAKI, A.-L. SKALTSOUNIS, A. ELFEKI, N. GHARSALLAH, N. ALLOUCHE.
    Preventive effects of oleuropein against cardiac remodeling after myocardial infarction in Wistar rat through inhibiting angiotensin-converting enzyme activity. Toxicology Mechanisms and Methods, 2015, 25, 538-546. DOI:10.1007/s12012-015-9323-1
  21. I. KHLIF, K. JELLALI, T. MICHEL, M. HALABALAKI, A.-L. SKALTSOUNIS, N.ALLOUCHE.
    Characteristics, phytochemical analysis and biological activities of extracts from Tunisian chetoui olea europaea variety. Journal of Chemistry, 2015, Article number 418731.
    http://dx.doi.org/10.1155/2015/418731
  22. I. VULCANO, M. HALABALAKI, A.-L. SKALTSOUNIS, M. GANZERA.
    Quantitative analysis of pungent and anti-inflammatory phenolic compounds in olive oil by capillary electrophoresis. Food Chemistry, 2015, 169, 381-6. DOI:10.1016/j.foodchem.2014.08.007
  23. K. VOUGOGIANNOPOULOU, C. LEMUS, M. HALABALAKI, C. PERGOLA, O. WERZ, A.B. SMITH, S. MICHEL, A.-L. SKALTSOUNIS, B. DEGUIN.
    One-Step Semisynthesis of Oleacein and the Determination as a 5-Lipoxygenase Inhibitor. Journal of Natural Products, 2014, 77, 441-5. DOI: 10.1021/np401010x
  24. A. KEILER, O. ZIERAU, R. BERNHARDT, N. LEMONAKIS, A. TERMETZI, A.-L. SKALTSOUNIS, G. VOLLMER, M. HALABALAKI.
    Impact of a functionalized olive oil extract on the uterus and the bone in a model of postmenopausal osteoporosis. European Journal of Nutrition, 2014, 53, 1073-1081. DOI:10.1007/s00394-013-0609-4
  25. E. ZOIDOU, P. MAGIATIS, E. MELLIOU, M. CONSTANTINOU, S.HAROUTOUNIAN , A.-L. SKALTSOUNIS.
    Oleuropein as a bioactive constituent added in milk and yogurt. Food Chem. 2014, 158, 319-324. DOI: 10.1016/j.foodchem.2014.02.137
  26. N. XYNOS, G. PAPAEFSTATHIOU, E. GIKAS, A. ARGYROPOULOU, N.ALIGIANNIS, A.-L.SKALTSOUNIS.
    Design optimization study of the extraction of olive leaves performed with pressurized liquid extraction using response surface methodology. Separation and Purification Technology, 2014, 122, 323-330.
    DOI:10.1016/j.seppur.2013.10.040
  27. I. ANDREADOU, E. MIKROS, K. IOANNIDIS, F. SIGALA, K. NAKA, S. KOSTIDIS, D. FARMAKIS, R. TENTA, N. KAVANTZAS, S.I. BIBLI, E. GIKAS, A.-L. SKALTSOUNIS, D.T. KREMASTINOS, E.K. ILIODROMITIS.
    Oleuropein prevents doxorubicin-induced cardiomyopathy interfering with signaling molecules and cardiomyocyte metabolism. J. Mol. & Cell. Cardiol, 2014, 69, 4-16. DOI:10.1016/j.yjmcc.2014.01.007
  28. M. SVOBODOVA, I. ANDREADOU, A.-L. SKALTSOUNIS, J. KOPECKY, P. FLACHS.
    Oleuropein as an inhibitor of peroxisome proliferator-activated receptor gamma. Genes and Nutrition, 2014, 9, Article number 376. DOI: 10.1007/s12263-013-0376-0
  29. N. LEMONAKIS, E. GIKAS, M. HALABALAKI, A.-L. SKALTSOUNIS.
    Development and Validation of a Combined Methodology for Assessing the Total Quality Control of Herbal Medicinal Products – Application to Oleuropein Preparations. PLOS ONE, 2013, 8, e78277. DOI: 10.1371/journal.pone.0078277 
  30. P. KANAKIS, A. TERMENTZI, T. MICHEL, E. GIKAS, M. HALABALAKI , A.-L. SKALTSOUNIS.
    From olive drupes to olive oil. An HPLC-Orbitrap-based qualitative and quantitative exploration of olive key metabolites. Planta Medica, 2013, 79, 1576-1587. DOI:10.1055/s-0033-1350823
  31. E.M. ODIATOU, A.-L. SKALTSOUNIS, A.-I. CONSTANTINOU.
    Identification of the factors responsible for the in vitro pro-oxidant and cytotoxic activities of the olive polyphenols oleuropein and hydroxytyrosol. Cancer Letters, 2013, 330, 113-121. DOI:10.1016/j.canlet.2012.11.035
  32. J.D. KYRIAZIS, N. ALIGIANNIS, P. POLYCHRONOPOULOS, A.-L. SKALTSOUNIS, E. DOTSIKA.
    Leishmanicidal activity assessment of olive tree extracts. Phytomedicine, 2013, 20, 275-281.
    DOI: 10.1016/j.phymed.2012.11.013
  33. M. KOSTOMOIRI, A. FRAGKOULI, M. SAGNOU, A.-L. SKALTSOUNIS, M. PELECANOU, E.-C. TSILIBARY, A.-K. ΤZINIA.
    Oleuropein, an Anti-oxidant Polyphenol Constituent of Olive Promotes α-Secretase Cleavage of the Amyloid Precursor Protein (AβPP). Cellular and Molecular Neurobiology, 2013, 33, 147-154.
    DOI: 10.1007/s10571-012-9880-9
  34. N. XYNOS, G. PAPAEFSTATHIOU, M. PSYCHIS, A. ARGYROPOULOU, N.ALIGIANNIS, A.-L. SKALTSOUNIS.
    Development of a green extraction procedure with super/subcritical fluids to produce extracts enriched in oleuropein from olive leaves. J. Supercrit. Fluids, 2012, 67, 89-93.
    DOI: 10.1016/j.supflu.2012.03.014
  35. E. ZOIDOU, E. MELLIOU, E. GIKAS, A. TSARBOPOULOS, P. MAGIATIS, A.-L. SKALTSOUNIS.
    Identification of ThroubaThassos, a traditional Greek table olive variety, as a nutritional rich source of oleuropein. J Agric Food Chem., 2010, 58, 46-50. DOI:10.1021/jf903405e
  36. I. ANDREADOU, E. ILIODROMITIS, E. MIKROS, A.-L. SKALTSOUNIS, D.. KREMASTINOS.
    The Usage of Oleuropein in the Myocardium. Olives and Olive Oil in Health Disease Prevention ed V.R. Preedy, Elsevier, 2010, 1433-1448.
  37. I. ANDREADOU, M. PAPAEFTHIMIOU, A. ZIRA, M. CONSTANTINOU, F. SIGALA, A.-L. SKALTSOUNIS, A. TSANTILI, E.-K. ILIODROMITIS, D.-T. KREMASTINOS, E. MIKROS
    Metabonomic identification of novel biomarkers in doxorubicin cardiotoxicity and protective effect of the natural antioxidant oleuropein. NMR Biomed., 2009, 22, 585-92. DOI:10.1002/nbm.1370
  38. C. PUEL, J. MARDON, A. AGALIAS, MJ DAVICCO, P. LEBECQUE, A. MAZUR, MN HORCAJADA, A.-L.. SKALTSOUNIS, V. COXAM.
    Major Phenolic Compounds in Olive Oil Modulate Bone Loss in an Ovariectomy/Inflammation Experimental Model. J. Agric Food Chem., 2008, 56, 9417-22. DOI:10.1021/jf801794q
  39. A. AGALIAS, P. MAGIATIS, A.-L. SKALTSOUNIS, E. MIKROS, A.TSARBOPOULOS, E. GIKAS, I. SPANOS, T. MANIOS.
    A new process for the management of olive oil mill waste water, recovering natural antioxidants. J. Agr. Food Chem., 2007, 55, 2671-2676. DOI:10.1021/jf063091d
  40. C. PUEL, J. MATHIEY, A. AGALIAS, S. KATI-COULIBALY, J. MARDON, C. OBLED, M. J. DAVICCO, P. LEBECQUE, M.-N. HORCAJADA, A.-L. SKALTSOUNIS, V. COXAM.
    Dose-response study of effect of oleuropein, an olive oil polyphenol, in an ovariectomyl/inflammation experimental model of bone loss in rat. Clinical Nutrition, 2006, 25, 859-868.
    DOI: 10.1016/j.clnu.2006.03.009
  41. F.BAZOTI, E. GIKAS, A.-L. SKALTSOUNIS, A. TSARBOPOULOS.
    Development of a Liquid Chromatography Electrospray Tandem Mass Spectrometry (LC-ESI MS/MS) Method for the Quantification of Bioactive Substances present in Olive Oil Mill Waste Waters. Analytica Chem. Acta, 2006, 573, 258-266. DOI: 10.1016/j.aca.2006.03.075
  42. I. ANDREADOU, E. ILIODROMITIS, A. AGALIAS, E. BOFILIS, A ZOGA, M. CONSTANTINOU, P. MAGIATIS, E.MIKROS, A.-L. SKALTSOUNIS, D. KREMASTINOS.
    Cardioprotective effect of a natural olive product, oleuropein, in normal and hypercholesterolemic rabbits. Journal of Nutrition, 2006, 136, 2213-2219.
    https://doi.org/10.1093/jn/136.8.2213